A flipper is an interim removable partial denture used for immediate esthetic restoration and space maintenance for a limited period before definitive treatment.Traditional methods for fabricating flippers are labor-intensive and manual.With the advent of technological advancement in dentistry, fully digitalized fabrication including computer desig

One of significant and, at the same time, challenging research problems in Economics is measuring the social effect of economic growth (development).Economic growth should never be treated a goal per se.It is rational provided that it brings effects such as, generally speaking, an improvement in the standard of living.However, this is not always th

Abstract Background A strong dose-volume relationship exists between the amount of small bowel receiving low- to intermediate-doses of radiation and the rates of acute, severe gastrointestinal toxicity, principally diarrhea.There is considerable interest in the application of highly conformal treatment approaches, such as intensity-modulated radiat

Medial ganglionic eminence (MGE)-derived parvalbumin (PV)+, somatostatin (SST)+and Neurogliaform (NGFC)-type cortical and hippocampal interneurons, have distinct molecular, anatomical, Denim and physiological properties.However, the molecular mechanisms regulating their maturation remain poorly understood.Here, via single-cell transcriptomics, we s

Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths worldwide due to high recurrence rates after curative treatment and being frequently diagnosed at an advanced stage.Immune-checkpoint inhibition (ICPI) has yielded impressive clinical successes in a variety of solid cancers, however results in treatment of HCC have